What is the most common germ cell tumor of the scrotum?

• A. Seminoma
• B. Embryonal carcinoma
• C. Choriocarcinoma
• D. Teratoma

Answer: (A)

Seminoma is the most common germ cell tumor of the testis, which is the same location as the scrotum in this context. It typically presents in young men as a painless scrotal mass. On ultrasound, it usually appears as a well-defined, homogeneous hypoechoic intratesticular lesion with internal vascularity on Doppler. Seminomata have an excellent prognosis and are highly radiosensitive. For tumor markers, pure seminomas normally do not elevate AFP, and only a minority may have a mild beta-hCG elevation if syncytiotrophoblastic cells are present. The other germ cell tumor types—embryonal carcinoma, choriocarcinoma, and teratoma—do occur but are less common and often have different marker patterns and behavior. Thus, seminoma is the best answer because it is the most prevalent germ cell tumor of the scrotum.