Which bilirubin fraction is unconjugated?

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Multiple Choice

Which bilirubin fraction is unconjugated?

Explanation:
Unconjugated bilirubin is the form produced from heme breakdown before the liver modifies it. It is lipid-soluble and travels in the bloodstream bound to albumin. In the liver, it is conjugated with glucuronic acid, producing the water-soluble, excretable form. This conjugated form is known as direct bilirubin. Delta bilirubin is a conjugated form that remains bound to albumin, not the unconjugated fraction. Bile acids are a different type of molecule altogether. Therefore, the unconjugated fraction corresponds to indirect bilirubin.

Unconjugated bilirubin is the form produced from heme breakdown before the liver modifies it. It is lipid-soluble and travels in the bloodstream bound to albumin. In the liver, it is conjugated with glucuronic acid, producing the water-soluble, excretable form. This conjugated form is known as direct bilirubin. Delta bilirubin is a conjugated form that remains bound to albumin, not the unconjugated fraction. Bile acids are a different type of molecule altogether. Therefore, the unconjugated fraction corresponds to indirect bilirubin.

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