Which pancreatic anomaly is caused by the failure of regression of the left ventral bud?

• A. Annular Pancreas
• B. Pancreatic Divisum
• C. Pancreatic Agenesis
• D. Ectopic Pancreatic Tissue

Answer: (A)

During pancreatic development, the organ forms from dorsal and ventral buds. The ventral bud normally rotates and fuses with the dorsal bud, and the left portion of the ventral bud regresses. If that regression fails, pancreatic tissue persists around the duodenum, creating a circular band of pancreas that encircles the second part of the duodenum. This ring of pancreatic tissue is known as annular pancreas and can lead to duodenal obstruction in newborns or present later with feeding difficulties.

Other listed conditions arise from different embryologic errors: pancreatic divisum results from failure of the dorsal and ventral ducts to fuse; pancreatic agenesis is the complete absence of pancreatic tissue; ectopic pancreatic tissue is pancreatic tissue located in an abnormal site outside the pancreas.